Evidence suggests that changes occurring in the natural environment due to the climate crisis are increasing the spread of infectious disease, including drug-resistant infections. AMR contributes to almost 5 million deaths annually, most of which are in low- and middle-income countries. Urgent action on AMR is critical to preserve our ability to treat human, animal and plant diseases, to reduce risks for food safety and secrurity, to protect the environment and to achieve the Sustainable Development Goals. Aligned with UNEP's publication 'Bracing for Superbugs,' the dialogue will explore environmental dimensions of AMR, with focus on the UNGA High-level Meeting on AMR in 2024. The Global Leaders Group on AMR will also launch its pocket guide on integrated surveillance.